Deadpool has become Americas sweetheart and thats all well and good.

The movies unprecedented ($700 million worldwide!)

success means thatDeadpool 2is definitely coming and well get more guest appearances all over the place.

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So just who are Deadpools villains?

Whos in the running to be in the sequels and whos being held back by rights issues?

I figured Id go through a whole lot of them.

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Now, two things before I get started: First, Im counting the actual supervillains.

Some random mob idiot who gets wasted in a two-issue Kid Deadpool arc doesnt really deserve mentioning.

Guys like Dr. Doom, Norman Osborn, Apocalypse, Carnage, and so on.

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Im only going to count those whose relationship with Deadpool is in some way tangible and important.

Hes a Weapon X experiment who worked alongside Deadpool, Garrison Kane, and Copycat.

Slayback also has a healing factor and it took ten years for him to put himself back together.

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Namely in the climax where Slayback mortally wounds Copycat as she tries to save Deadpool.

An android named Adam activates and wipes out Slayback completely due to his violent, irredeemable nature.

Slayback would return many years later during the final arc of Daniel WaysDeadpoolrun.

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Hes basically a non-factor and gets blown up yet again.

It looks like third times a charm, since hes last shown in Hell.

Whats important is that they make for a pretty interesting fighting dynamic.

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Deadpool can only evade Juggernaut.

Through violence, he simply cant dent the big lug.

Juggernauts only weakness is his teammate.

They would make for good movie foes, especially to tag-team Deadpool and Cable.

Juggernaut, like Deadpool, is a previously-usedX-Mencharacter in that movie franchise who could really use a second shot.

Black Box was definitely a step up from that one.

Black Box is like a cross between Professor Xavier and Cyborg.

I suppose digital telepath is the best way to describe him.

Black Box plays on the side of the angels until being slaughtered by Sabretooth.

Later he appears alive and well, aware and interested when Deadpool has lost his healing factor.

Black Box stops after Black Swan makes him forget about Deadpools vulnerability.

In the comics, Killbrew was the scientist responsible for creating Deadpool with Ajax as his sadistic orderly.

Killbrew was a callous sort who had no qualms in torturing Wade to get results.

During the Joe Kelly run, Killbrew is reintroduced in a different light.

Hes trying to make amends for the horrors of his past and even helps Deadpool out a couple times.

Deadpool tries to kill him, though he gets talked down.

Kelly introduced him as the main antagonist of his run and heshouldhave become Deadpools Joker/Luthor/Green Goblin/Magneto.

T-Ray is a mercenary rival of Deadpools who uses both his enhanced strength and skills in dark magic.

Hes far more ruthless than Deadpool and has a knowing interest in watching Deadpools failures.

His tendency to antagonize Deadpool turns out to be a justifiable case of wanting revenge.

See, T-Ray is Wade Wilson.

Deadpool is Jack, a mercenary who was once taken in by Wade and Mercedes Wilson.

The trauma caused him to go nuts and he believed himself to actually be Wade.

Thus brings the moral of Kellys run, which would make agreatheart for a sequel.

Deadpool at least strives to be a better person, even if past crimes make it hopeless.

A fellow high-ranking merc, Taskmaster has had many run-ins with Deadpool, both with and against.

Deadpool ends up being an outlier against his abilities in the sense that Taskmaster cant predict his movements.

For a time, Fox did have the rights to Taskmaster as his own property.

Sadly, the rights have lapsed already and he cannot show up in theX-Mencinematic universe.

More specifically, she raped him.

Betting on Mary turns out to be a big mistake as shes a lost cause.

She later comes back to him and they sleep with each other.

This Arcade knockoff has appeared in a single issue where he proceeded to not get his comeuppance.

Hes a high-class serial killer whos fallen in love with the art of killing people through creative traps.

He takes an interest in Deadpool due to his unkillable nature and proceeds to mess with him.

Instead of being an honorable samurai warrior, Wade Wilson was a great sumo wrestler.

While in Japan, someone got a hold of his DNA and created a dwarf clone of him.

The ridiculous and tiny assassin Widdle Wade is also accompanied by an equally-ridiculous talking dog named Daruma.

Widdle Wade is only made from his genetics and lacks both his healing factor and bodily scars.

At the same time, he has inherited his bloodlust, but forgives Deadpool for it before dying.

Originally called the Attending, Francis was there for Wades transition into a metahuman psychopath at Weapon X.

He seeks and destroys other Weapon X experiments before going after Deadpool.

Ajax would appear occasionally in flashbacks and manic episodes.

The miniseriesDeadpool vs. Thanoshas him resurrected, but within another issue, hes swept off the board yet again.

The weird thing is that its their friendship that humanizes Bullseye more than anything else in comics.

Too bad hes a Daredevil property.

The problem is that an alien warrior called Tiamat is out to intercept the being.

Tiamat wanders off, distraught and angry over having his own purpose stolen by another.

This is kind of awkward.

Yes, Vanessa prostitute with a heart of gold is considered a Deadpool rogue.

Deadpool was her abusive ex-boyfriend and she ended up partnering up with Garrison Kane for a while.

Then Deadpool became a more heroic character.

For a while, Deadpool lived in an apartment with villain roommates Constrictor and Titania.

Later it was discovered that all this time, Titiania was just Copycat in disguise, working against Wade.

Deadpool later admitted that he knew they were her and wanted her to get help.

Then Deadpool came to realize that he still had feelings for her and they briefly got back together.

Unfortunately, Vanessa was still a bit deranged and took out her jealousy on Siryn before leaving Wade.

Their killing spree leads to a high reward and that brings Deadpool into the game.

His first run-in with them ends badly as the two girls crush him between two cars head-on.

Fittingly, Grace gives her a mercy killing later.

Deadpool leaves the team to go protect Copycat and ultimately fails.

Sabretooth kills her and Deadpool is melted into goo by Weapon X.

He eventually comes back, but he never gets his revenge.

In fact, they never bring it up ever again.

Deadpools crossed paths with Sabretooth many times and the whole, You killed my girlfriend!

incident has never, ever been alluded to.

Even while Deadpool is riddling the mutant with hundreds of bullets.

Hes a dandy German mercenary with exceptional killing skills as well as telepathic abilities.

Deadpool unknowingly takes credit for Swans magnum opus assassin hit and becomes a huge name in the merc circles.

Bigger than before, at least.

Swan uses his telepathy to slowly erode Deadpools brain.

Swan does eventually fix Deadpools brain, but while doing so, he amplifies his own powers.

Black Swan does come back anyway in a Daniel Way story, though theres zero explanation.

Hit-Monkey hates all mafia types, especially killers, and has targeted Deadpool from time to time.

Now he works for the government and kills monsters with a robotic Dum Dum Dugan.

White Lightnin is a large redneck of limited intelligence who can control electricity.

Since he cantcreateelectricity, he simply covers himself with a handful of car batteries and duct tape.

He acts as an enforcer to the local corrupt police and is taken down by Deadpools intervention.

Naturally, Deadpool recovers.

Macho has yet to cross paths with Deadpool again, though he has teamed up with Rocket Raccoon elsewhere.

The two have admitted that Deadpool is way craftier than he looks.

At least, I think its intentional.

For instance, it turns out that she keeps dismembered pieces of Deadpool in her refrigerator.

Theres something kind of icky about it.

Then again, look at his unmasked Wade.

He looks like a regular, bald man who got cold soup poured on his head.

I guess Barberi just cant draw ugly people.

Hes taken down in the end by a dart that undoes his healing factor and allows him to die.

Regular Deadpool ends up getting his hands on that formula so he himself is able to die.

She was undercover and a Deadpool hit led to her being caught in an explosion thats rendered her tetraplegic.

While unable to move, she does have a keen mind thats able to predict Deadpools actions.

She puts together a team of Slayback and T-Ray, although they fail to complete the job.

Years ago, back during Tony Starks drunken days, Vetis hired Deadpool to confirm Iron Man stayed drunk.

By collecting all at once, hell have the might to challenge Mephisto.

Vetis has yet to appear again, but Deadpool takes the threat of his potential return extremely seriously.

Their target was the White Man, an albino pimp whose name came with a million easy jokes.

He was armed with a magic pimp cane that could turn its victims to stone.

As for the White Man, his cane was used against him, turning him into a statue.

Years pass and hes freed from his imprisonment.

He takes hostages in hopes of getting revenge, but the three heroes dont even remember him.

The White Man is freed eventually…1,000 years later.

Hes thrown into an alien museum.

Too bad Butler was trying to use his findings for darker purposes.

All the while, hed experiment on Deadpool and cut out more organs.

Hes also kidnapped Carmelita and her daughter Ellie in case Deadpool was to go after him.

Deadpool eventually tracks down and kills Butler thanks to the help from Butlers long-suffering sister.

Even though Butler is dead, the horrors of his deeds are still being unearthed.

Deadpool still hasnt found out about that yet and the truth will likely destroy him.

The two would be wed as a royal thing to bring peace to the monster kingdom.

Two things happen to muck that up.

First, Dracula realizes that he doesnt actually need to marry Shiklah after all and has her siblings slaughtered.

Second, Deadpool and Shiklah fall for each other and even get married before facing him.

He escapes, swearing to get his revenge.

A fast-forward into the year 2099 shows that she and Deadpool are destined to have a daughter together.

A Captain America villain whos insane, chaotic, unkillable, amoral, hideous, and silly.

The two do meet up in the 90s during a near-forgottenHeroes for Hirestoryline.

During Daniel Ways lengthyDeadpoolrun, Deadpool has two voices in his head, constantly talking to him.

Madcaps since been separated, but the separation anxiety has made him jealous and aggravated.

Although hes disposed of for the moment, Madcap continues to haunt Deadpool.

He tosses in a bunch of names from each characters history and builds on that.

Then Nicieza does a digital series calledSplit Secondand finally creates a new bad guy.

Theres an incident where his son Darius is killed.

Deadpool fixes everything, including the gnarly stuff going on in Cables backstory.

Yes, thats the gist version.

Hes had his share of run-ins with Deadpool, mainly because of Wolverine being involved.

All in all, nothing especially notable or memorable on its own merits.

Beyond that, Deadpool and Daken make great foils for each other as second-generation Logans.

Just as long as we dont have Wade and Cable fight Stryfe.

We deserve better than that.